Fluge and Mella used an expensive bit of kit called the Seahorse analyser, which measures glycolysis through the lactate production and mitochondrial activity through changes in oxygen levels.
They tested normal healthy muscle cells that had been grown in the lab. But they added to those cells serum taken from either ME/CFS patients or healthy controls. Serum is the fluid left over after blood has clotted and it contains small molecules and other soluble substances.
They have data for 12 people with ME/CFS and 12 healthy controls, a relatively small sample.What they found was, surprisingly, that the muscle cells produced more lactate and burned more oxygen when they were incubated with ME/CFS serum than when incubated in serum from healthy controls. And the effect was particularly strong when the cells were made to work hard.
The article doesn’t say it but I will: fuck John Walker, Jr.
In 1968 one of the U.S. Navy’s nuclear submarines went missing in the Atlantic. Now, 50 years later, the full story of its disappearance can finally be told.RADIOMEN 2ND CLASS MIKE HANNON WALKED TO WORK WITH A PALPABLE SENSE OF UNEASE on the morning of May 23, 1968. As a communications specialist at Submarine Force Atlantic Headquarters, he was responsible for processing dozens of messages each day from submarines at sea, ranging from routine announcements to top-secret operational dispatches. But hours earlier, when his eight-hour shift had ended at midnight, Hannon feared that one of the submarines on his watch might be in trouble—or worse.
The Norfolk-based USS Scorpion, one of the Atlantic Fleet’s 19 nuclear attack submarines, had been scheduled to transmit a four-word “Check Report”—encrypted to prevent the Soviets from intercepting it—that meant, in essence, “Situation normal, proceeding as planned.” In this instance, the Skipjack-class submarine was returning to Norfolk after a three-month deployment to the Mediterranean Sea. Its standing orders called for a burst transmission every 24 hours that, when decrypted, read: “Check 24. Submarine Scorpion.” But the previous day no message had come clattering out of the secure teletypewriter that Hannon used. As he prepared to leave for the night, Hannon had briefed Radioman 2nd Class Ken Larbes, the petty officer coming on duty, about the overdue message. He then tapped on his supervisor’s office door and asked whether any late word had come in from the Scorpion. Warrant Officer John A. Walker Jr. silently shook his head no. Was this the first hint of an emergency, Hannon wondered, or merely a delayed transmission caused by mechanical problems or stormy weather conditions?
I was searching for stuff on my computer tonight when I came across a diary entry I created back on my 28th birthday, 21 Jan 1997. I had started journaling then mainly because I had started having trouble with my memory. It is also why I began this blog, as I’ve said before.
This entry is from a time when I was young, single, fit, and supposedly at the top of my game, yet I was deeply concerned about my future. I post it today to remind myself of just how long I’ve been dealing with Gulf War Illness.
It has been three decades of pain and frustration but I am still here.
Looking at the old clock on the wall I see that I’ve just turned 28 years old. Here I am sitting at my keyboard on my 28th birthday, all alone save for a lazy cat. I didn’t feel like staying at the party because I’m feeling down, so I guess I really didn’t have to be alone. I can’t talk to those guys about what’s bothering me because they couldn’t relate. There are very few people who could. But the party was getting my down because I couldn’t seem to jump-start myself into the conversation, and I became alarmed at this inability to speak.
On November 7, 1992, a really passionate Rage Against the Machine performed an incredible show at Berkeley Square in Berkeley, California. This powerful set included some of their now iconic songs such as “Bombtrack”, “Fistful Of Steel”, “Wake Up”, “Settle For Nothing” , “Killing In The Name”, “Bullet In The Head” and “Freedom”.
Commenter Mike4Metal was at this show and shared his excitement about seeing the band that night.
I was there that night!! The organization opened up that night, no one knew who rage was at this time, their debut was not out yet!! They surprised us all that night!!! I feel lucky to have witnessed their first Bay Area gig!!! Now they are legendary!!!
Earlier that year, the band performed an equally incredible show at Zed Records in Long Beach.
Rocket was absolutely the chillest dog you would ever meet. He rarely got excited, wasn’t nervous except around thunderstorms or fireworks, and pretty much got along well with anyone, man or beast. Strangers came and went all throughout our recent home renovation and many times Rocket wouldn’t bother to lift his head.
If you could imagine a low maintenance pet, Rocket was it. I can think of only one time in the entire eleven years he lived with us that he peed in the house – and that was my fault for not reading his signals. Some of that is his fault, though, because his signal for needing to go outside was always to stand quietly in front of the door. If you weren’t paying attention you would miss it!
We brought Rocket home from the Lab Rescue of North Carolina group after seeing his photo on their website. A rescue volunteer brought him over on Travis’s fourth birthday (October 2008) so we could see how he fit into the family. Rocket immediately made himself at home, winning our hearts. It was clearly a good match.
The wonders of Facebook has connected me with new friends and reconnected me with old. It has allowed me to connect with people I would’ve given up for “lost” just ten years ago. I have been especially happy to rekindle friendships made while I served in the U.S. Navy aboard USS Elliot DD-967. There is nothing like the bond built by shipmates, forged in the unforgiving environment of the sea.
My shipmates are family, and like families everywhere we may have our differences but there’s no denying that bond. This brings me to my friend Robert P. Nordman.
Nordman, as I called him, joined Elliot about the time I did. He was trained as a Gas Turbine Systems Electrician Fireman (GSEFN) – an engineer or “snipe” as they’re proudly known. Nordman and I worked on completely different levels of the ship, him workspace being the engine room and mine the topmost deck of the ship. Still, I would joke with him on the messdecks, chat on the fantail during a break, or see him out on liberty. More often than not, though, Nordman would be late for liberty (or miss it altogether) because of the demands of his job. He would spend a lot of his liberty either preparing the ship to depart or preparing it to be in port.
RADM Kevin Sweeney stepped down as SECDEF chief of staff this weekend. I served with Sweeney when he was a mere lieutenant serving as Combat Systems Officer (CSO) on the USS Elliot DD-967. Though some considered him an “arrogant prick,” Sweeney seemed to me to be a brusque-yet-squared-away sailor and I have been pleased to learn of his career success.
Rear Admiral Kevin Sweeney, USN (Ret.), has stepped down as Chief of Staff to the Secretary of Defense. He has served in this role since January 2017. “After two years in the Pentagon, I’ve decided the time is right to return to the private sector. It has been an honor to serve again alongside the men and women of the Department of Defense,” said Sweeney.
Hours of toiling with Google Earth (GE) has allowed me to get a good feel for how the 1865 map of Raleigh’s breastworks matches up to local landmarks. I created an image overlay in GE, then marked with a pushpin landmarks that are still around today. A bit (okay, hours) of stretching and rotating the overlay image got me a close match of where things were as compared to today.
After messing with Google Earth for hours tonight I finally got a rough idea of the location of one of Raleigh’s Civil War “camps of instruction,” Camp Holmes. It seems to have been west of the modern-day intersection of Capital Boulevard and Wake Forest Road, where the Raleigh Bonded warehouses and Norfolk Southern’s Raleigh Yard are today. Being that most of the camp is now a railyard, poking around there is not feasible. Still, there might be interesting finds on the periphery, perhaps the treeline south of Georgetown Road.
Who knew that those dingy warehouses and railyard was once the site where 9,000 Confederate conscripts trained to become soldiers?
A friend shared a historical map this morning that caught my eye. It is a map of the old breastworks built by the city of Raleigh to impede approaching Union troops near the end of the Civil War. I’d seen the historical marker (H-30) a mile away from my home, mentioning that breastworks were nearby but I’d never seen them and didn’t think much about them until now. So, one of my upcoming projects is to trace the path of the old earthen walls so that I can visit these sites to see if there’s anything left (update: found them!). After 153 years, it’s unlikely I’ll find any remnants of the five-foot-tall earthen walls and gravel but you never know.
Another detail of the map caught my eye, however: Camp Holmes. Curious about what this is, I did a few Google searches and was surprised to learn that nobody really knows where it was. It’s plainly on this old map, however, so a bit of Google Earth magic should show me roughly where I can physically search for it (update: found it!)
My Camp Holmes searches brought up a few lonely hits, one of which is a letter detailing an inspection made of Camp Holmes by Confederate assistant adjutant-general LtC Archer Anderson in June 1864. It provides an interesting look at the camp. There are others online, too, in the form of handwritten letters which will take some deciphering before being posted online.
As the letter appeared in a US Congressional publication in 1900 it is now in the public domain. Here it is in its entirety. I’ll post more stories as I learn more about the camp.
June 16, 1864.
Report of inspection of Camp Holmes, a camp of instruction near Raleigh, commanded by Major Hahr, with the following: staff: One first lieutenant, adjutant; one first lieutenant, receiving officer; one assistant quartermaster; one assistant commissary of subsistence; one surgeon and one assistant surgeon; one chaplain; one first lieutenant, commanding guard; four second lieutenants, drill-masters.